BBC3
BCL2 binding component 3
Synonimy:
JFY-1, JFY1, PUMA
Gatunek:
Human BBC3 (27113), Mouse Bbc3 (170770), Rat Bbc3 (317673), dog BBC3 (612153), Zebrafish bbc3 (751763), domestic guinea pig Bbc3 (101788977), naked mole-rat Bbc3 (101714844), cow BBC3 (782359)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(27113) Summary: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
- Mouse(170770) BCL2 binding component 3
- Rat(317673) Bcl-2 binding component 3
- dog(612153) BCL2 binding component 3
- Zebrafish(751763) BCL2 binding component 3
- domestic guinea pig(101788977) BCL2 binding component 3
- naked mole-rat(101714844) BCL2 binding component 3
- cow(782359) BCL2 binding component 3
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PUMA/bbc3, N-Terminal antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
microarray
western blot
western blot
Monoclonal Anti-PUMA antibody produced in mouse, clone 10C5G1, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, rat
Zastosowanie
ELISA
western blot
western blot
Monoclonal Anti-PUMA antibody produced in mouse, clone 2A9G5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Przeciwciało przeciwko domenie BH3 pumy, from rabbit,
Reaktywność gatunkowa
mouse
Zastosowanie
western blot
Anty-PUMA, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot