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CBX5

chromobox homolog 5

Synonimy:
HP1, HP1A
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(23468) Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12419) chromobox 5
  • Rat(300266) chromobox homolog 5
  • sheep(100307036) chromobox homolog 5
  • naked mole-rat(101710464) chromobox homolog 5
  • domestic guinea pig(100727253) chromobox homolog 5
  • cow(538885) chromobox homolog 5
  • dog(477593) chromobox homolog 5
  • Zebrafish(563396) chromobox homolog 5 (HP1 alpha homolog, Drosophila)
  • domestic cat(101091461) chromobox homolog 5

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-CBX5 antibody produced in mouse, clone 1E11-3A10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

western blot
Anti-CBX5 Antibody, clone 5I2-K ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Przeciwciało anty-HP1α, klon 15.19s2, clone 15.19s2, Upstate®, from mouse,
Reaktywność gatunkowa
human, mouse, vertebrates
Zastosowanie
ChIP
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Heterochromatin Protein-1 α Antibody, clone 2HP-2G9, ascites fluid, clone 2HP-2G9, Chemicon®,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunoprecipitation (IP)

western blot
Rabbit anti-CBX5 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CBX5,
Gatunek
human
MISSION® esiRNA, targeting mouse Cbx5,
Gatunek
mouse