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Merck

CSTB

cystatin B (stefin B)

Synonimy:
CST6, EPM1, EPM1A, PME, STFB, ULD
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1476) Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008]
  • Mouse(13014) cystatin B
  • Rat(25308) cystatin B (stefin B)
  • domestic guinea pig(100719016) cystatin B (stefin B)
  • naked mole-rat(101699171) cystatin B (stefin B)
  • cow(514170) cystatin B (stefin B)
  • cow(512805) cystatin B (stefin B)
  • dog(478424) cystatin B (stefin B)
  • chicken(418267) cystatin B (stefin B)
  • sheep(101123265) cystatin B (stefin B)

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human Cystatin B ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-CSTB antibody produced in mouse, clone M1-C1, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-CSTB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anty-CSTB, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Proteins

Numer produktu
Opis
Gatunek
Cystatin B human, recombinant, expressed in E. coli,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CSTB,
Gatunek
human
MISSION® esiRNA, targeting mouse Cstb,
Gatunek
mouse