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Merck

CYBB

cytochrome b-245, beta polypeptide

Synonimy:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Gatunek:
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), cow CYBB (281112), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801), dog CYBB (491825), chicken CYBB (418581), Zebrafish cybb (393386)
Identyfikator UniProtKB:
P04839, A8K138, Q2PP16
Identyfikator genu:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
ZRB2447
Anti-NOX2/gp91phox Antibody, clone 1J16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
07-024
Przeciwciało anty-gp91-phox, Upstate®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
western blot
AV44276
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rabbit, rat
Zastosowanie
western blot
SAB5702937
Przeciwciało anty-NOX2/gp91phox, klon 2Y8W3, królicze monoklonalne, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
SAB4300724
Anty-CYBB, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU010941
MISSION® esiRNA, targeting human CYBB,
Gatunek
human