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FGF8

fibroblast growth factor 8 (androgen-induced)

Synonimy:
AIGF, FGF-8, HBGF-8, HH6, KAL6
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2253) Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(14179) fibroblast growth factor 8
  • Rat(29349) fibroblast growth factor 8
  • chicken(396313) fibroblast growth factor 8 (androgen-induced)
  • domestic cat(101084652) fibroblast growth factor 8 (androgen-induced)
  • dog(403868) fibroblast growth factor 8 (androgen-induced)
  • sheep(101113716) fibroblast growth factor 8 (androgen-induced)
  • cow(326284) fibroblast growth factor 8 (androgen-induced)
  • Domestic Rabbit(100008834) fibroblast growth factor 8 (androgen-induced)
  • naked mole-rat(101699438) fibroblast growth factor 8 (androgen-induced)
  • domestic guinea pig(100721355) fibroblast growth factor 8 (androgen-induced)

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-FGF8 antibody produced in mouse, clone 2A11, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
proximity ligation assay
Monoclonal Anti-FGF8 antibody produced in mouse, clone 3H2, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Mysz anty-FGF8 mAb (2A10), liquid, clone 2A10, Calbiochem®,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie

Proteins

Numer produktu
Opis
Gatunek
Fibroblast Growth Factor-8b from mouse, >97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder,
Gatunek
mouse

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Fgf8,
Gatunek
mouse