HDAC8
histone deacetylase 8
Synonimy:
CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
Gatunek:
Human HDAC8 (55869), Mouse Hdac8 (70315), Rat Hdac8 (363481), domestic guinea pig Hdac8 (100721893), chicken HDAC8 (422182), Zebrafish hdac8 (406740), domestic cat HDAC8 (101096383), dog HDAC8 (480957), sheep HDAC8 (101110121), cow HDAC8 (540666)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(55869) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(70315) histone deacetylase 8
- Rat(363481) histone deacetylase 8
- domestic guinea pig(100721893) histone deacetylase 8
- chicken(422182) histone deacetylase 8
- Zebrafish(406740) histone deacetylase 8
- domestic cat(101096383) histone deacetylase 8
- dog(480957) histone deacetylase 8
- sheep(101110121) histone deacetylase 8
- cow(540666) histone deacetylase 8
- naked mole-rat(101697998) histone deacetylase 8
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti Histone deacetylase 8 Antibody, clone 23GB6185, Rabbit Monoclonal, clone 23GB6185, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti Histone deacetylase 8 Antibody, clone 23GB6180, Rabbit Monoclonal, clone 23GB6180, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
[Zatwierdzone przez KO] Przeciwciało anty-HDAC8, klon 1O2Y5, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Przeciwciało anty-HDAC8, serum, Upstate®,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
Proteins
Numer produktu
Opis
Gatunek
HDAC-8 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Gatunek
human