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IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

Synonimy:
IMPD2, IMPDH-II
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
  • Mouse(23918) inosine 5'-phosphate dehydrogenase 2
  • Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
  • domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti IMPDH2 Antibody, clone 23GB6670, Rabbit Monoclonal, clone 23GB6670, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
western blot
Anti-IMPDH2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunoprecipitation (IP)

western blot
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Mysz anty-IMPDH2 mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
Reaktywność gatunkowa
human
Zastosowanie

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
β-Nicotinamide adenine dinucleotide, reduced dipotassium salt, ,
Gatunek
human
Mycophenolate mofetil, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Mycophenolic acid solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Mycophenolate Mofetil, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Mycophenolate mofetil, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
Inosine Monophosphate Dehydrogenase Type II human, recombinant, expressed in E. coli,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human IMPDH2,
Gatunek
human
MISSION® esiRNA, targeting mouse Impdh2,
Gatunek
mouse