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Merck

IPO7

importin 7

Synonimy:
Imp7, RANBP7
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(10527) Summary: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008]
  • Mouse(233726) importin 7
  • Rat(308939) importin 7
  • chicken(423046) importin 7
  • Zebrafish(321739) importin 7
  • sheep(101105184) importin 7
  • cow(513707) importin 7
  • Horse(100055677) importin 7
  • domestic cat(101091652) importin 7
  • dog(485383) importin 7
  • naked mole-rat(101702324) importin 7
  • domestic guinea pig(100731817) importin 7
  • Domestic Rabbit(100345214) importin 7

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-IPO7, (C-terminal) antibody produced in mouse, clone 4G6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-IPO7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-IPO7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Ipo7,
Gatunek
mouse
MISSION® esiRNA, targeting human IPO7,
Gatunek
human