LAT
linker for activation of T cells
Synonimy:
LAT1, pp36
Gatunek:
Human LAT (27040), Mouse Lat (16797), Rat Lat (81511), fruit fly lat (36454), Zebrafish lat (100233211), dog LAT (607947), domestic cat LAT (101093319), cow LAT (514735), sheep LAT (101110725), domestic guinea pig Lat (100723774)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(27040) Summary: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(16797) linker for activation of T cells
- Rat(81511) linker for activation of T cells
- fruit fly(36454) latheo
- Zebrafish(100233211) linker for activation of T cells
- dog(607947) linker for activation of T cells
- domestic cat(101093319) linker for activation of T cells
- cow(514735) linker for activation of T cells
- sheep(101110725) linker for activation of T cells
- domestic guinea pig(100723774) linker for activation of T cells
- naked mole-rat(101711455) linker for activation of T cells
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-LAT (Tyr220) Antibody, clone 24GB1375, Rabbit Monoclonal, clone 24GB1375, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Przeciwciało anty-LAT, klon 2E9, clone 2E9, Upstate®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunoprecipitation (IP)
western blot
western blot
Przeciwciało anty-fosfo-LAT, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-LAT1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Przeciwciało anty-fosfo-LAT-Y171wytwarzane u królika, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Proteins
Numer produktu
Opis
Gatunek