MAP2K1
mitogen-activated protein kinase kinase 1
Synonimy:
CFC3, MAPKK1, MEK1, MKK1, PRKMK1
Gatunek:
Human MAP2K1 (5604), Mouse Map2k1 (26395), Rat Map2k1 (170851), domestic guinea pig Map2k1 (100712888), dog MAP2K1 (478347), Horse MAP2K1 (100065996), domestic cat MAP2K1 (101081387), chicken MAP2K1 (415549), naked mole-rat Map2k1 (101715628), cow MAP2K1 (533199) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(5604) Summary: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
- Mouse(26395) mitogen-activated protein kinase kinase 1
- Rat(170851) mitogen activated protein kinase kinase 1
- domestic guinea pig(100712888) mitogen-activated protein kinase kinase 1
- dog(478347) mitogen-activated protein kinase kinase 1
- Horse(100065996) mitogen-activated protein kinase kinase 1
- domestic cat(101081387) mitogen-activated protein kinase kinase 1
- chicken(415549) mitogen-activated protein kinase kinase 1
- naked mole-rat(101715628) mitogen-activated protein kinase kinase 1
- cow(533199) mitogen-activated protein kinase kinase 1
- Domestic Rabbit(100009316) mitogen-activated protein kinase kinase 1
- sheep(101123635) mitogen-activated protein kinase kinase 1
- Zebrafish(406728) mitogen-activated protein kinase kinase 1
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ELISA
Numer produktu
Opis
Gatunek
Phospho-Mek (pSer217 / 221) ELISA Kit, for detection of phospho-mek (pSer217 / 221) in human, mouse or rat cell and tissue lysates,
Gatunek
human
Phospho-Mek (pSer217 / 221) and pan-Mek ELISA Kit, for detection of phospho-mek (pSer217 / 221) and pan-mek in human, mouse or rat cell and tissue lysates,
Gatunek
human
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MEK1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MEK1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-MAP2K1 antibody produced in mouse, clone 1B5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Anti-MAP2K1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Przeciwciało anty-MEK1, klon 6B7.1, clone 6B7.1, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Small Molecule - Inhibitor
Numer produktu
Opis
Gatunek
U0126, U0126 is a elective inhibitor of MEK-1 and MEK-2; weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4.,
Gatunek
human
Proteins
Numer produktu
Opis
Gatunek
Białko MEK1, nieaktywne, 50 g, Unactive, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
Gatunek
human
Białko MEK1, aktywne, 10 µg, Active, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
Gatunek
human
MEK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
mouse