MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
Synonimy:
MARCH-I, RNF171
Gatunek:
Human MARCH1 (55016), Mouse March1 (72925), Rat March1 (361135), sheep MARCH1 (101106078), naked mole-rat March1 (101724772), domestic guinea pig March1 (100722498), chicken MARCH1 (422420), dog MARCH1 (612618), domestic cat MARCH1 (101098865), cow MARCH1 (617247)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(55016) Summary: MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]
- Mouse(72925) membrane-associated ring finger (C3HC4) 1
- Rat(361135) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- sheep(101106078) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- naked mole-rat(101724772) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- domestic guinea pig(100722498) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- chicken(422420) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- dog(612618) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- domestic cat(101098865) membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
- cow(617247) membrane-associated ring finger (C3HC4) 1
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MARCH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-MARCH1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Monoclonal Anti-MARCH1 antibody produced in mouse, clone 3D2, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA