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PRKCQ

protein kinase C, theta

Synonimy:
PRKCT, nPKC-theta
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5588) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
  • Mouse(18761) protein kinase C, theta
  • Rat(85420) protein kinase C, theta
  • cow(505901) protein kinase C, theta
  • Zebrafish(555521) protein kinase C, theta
  • Horse(100070207) protein kinase C, theta
  • domestic guinea pig(100726308) protein kinase C, theta
  • naked mole-rat(101724103) protein kinase C, theta
  • domestic cat(101100730) protein kinase C, theta
  • dog(478013) protein kinase C, theta
  • chicken(776459) protein kinase C, theta
  • sheep(101113426) protein kinase C, theta

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PRKCQ antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-phospho-PKC θ (pThr538) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Przeciwciało anty-fosfo-PRKCQ-T538wytwarzane u królika, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti PKC theta Antibody, clone 23GB4105, Rabbit Monoclonal, clone 23GB4105, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
immunofluorescence

western blot
Anti-PKCθ Antibody, clone 2N22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse, nonhuman primates, rat, sheep
Zastosowanie
affinity binding assay
immunocytochemistry

immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
UCN-01, ≥97% (HPLC), powder,
Gatunek
human
GSK690693, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala, ,
Gatunek
mouse
Białko PKC θ, aktywne, 10 µg, Active, recombinant full-length human PKC theta with a C-terminal 6His-tag. For use in Kinase Assays.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PRKCQ,
Gatunek
human
MISSION® esiRNA, targeting mouse Prkcq,
Gatunek
mouse