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Merck

RAPGEF5

Rap guanine nucleotide exchange factor (GEF) 5

Synonimy:
GFR, MR-GEF, REPAC
Gatunek:
Human RAPGEF5 (9771), Mouse Rapgef5 (217944), Rat Rapgef5 (362799), domestic guinea pig Rapgef5 (100733128), dog RAPGEF5 (482349), Domestic Rabbit RAPGEF5 (100337732), chicken RAPGEF5 (100857462), naked mole-rat Rapgef5 (101700232), Horse RAPGEF5 (100067593), cow RAPGEF5 (519566) ...Więcej
Identyfikator UniProtKB:
Q92565, A4D140, Q8IXU5
Identyfikator genu:
  • Human(9771) Summary: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]
  • Mouse(217944) Rap guanine nucleotide exchange factor (GEF) 5
  • Rat(362799) Rap guanine nucleotide exchange factor (GEF) 5
  • domestic guinea pig(100733128) Rap guanine nucleotide exchange factor (GEF) 5
  • dog(482349) Rap guanine nucleotide exchange factor (GEF) 5
  • Domestic Rabbit(100337732) Rap guanine nucleotide exchange factor (GEF) 5
  • chicken(100857462) Rap guanine nucleotide exchange factor (GEF) 5
  • naked mole-rat(101700232) Rap guanine nucleotide exchange factor (GEF) 5
  • Horse(100067593) Rap guanine nucleotide exchange factor (GEF) 5
  • cow(519566) Rap guanine nucleotide exchange factor (GEF) 5
  • sheep(101108303) Rap guanine nucleotide exchange factor (GEF) 5
  • domestic cat(101088478) Rap guanine nucleotide exchange factor (GEF) 5

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
HPA057821
Anti-RAPGEF5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
HPA076772
Anty-RAPGEF5, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot