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Merck

RRM1

ribonucleotide reductase M1

Synonimy:
R1, RIR1, RR1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(6240) Summary: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]
  • Mouse(20133) ribonucleotide reductase M1
  • Rat(685579) ribonucleotide reductase M1
  • chicken(419081) ribonucleotide reductase M1
  • Zebrafish(30740) ribonucleotide reductase M1 polypeptide
  • dog(476823) ribonucleotide reductase M1
  • cow(505537) ribonucleotide reductase M1
  • Horse(100053126) ribonucleotide reductase M1
  • domestic cat(101097343) ribonucleotide reductase M1
  • Domestic Rabbit(100345823) ribonucleotide reductase M1
  • sheep(101116171) ribonucleotide reductase M1
  • naked mole-rat(101708047) ribonucleotide reductase M1
  • domestic guinea pig(100728488) ribonucleotide reductase M1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-RRM1, klon 4P4U1, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anty-RRM1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anty-RRM1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-RRM1 Antibody, clone 1E20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey
Zastosowanie
affinity binding assay
flow cytometry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Hydroxycarbamide, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Hydroxycarbamide, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Hydroxyurea, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Hydroxyurea, 98%, powder,
Gatunek
human
Gemcitabine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human RRM1,
Gatunek
human
MISSION® esiRNA, targeting mouse Rrm1,
Gatunek
mouse