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1332000

USP

Hydroxyurea

Name: Hydroxyurea
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonim(y):

Hydroxycarbamide

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Rozmiar/SKU	Dostępność	Cena netto

Informacje o tej pozycji

Wzór liniowy:

NH₂CONHOH

Numer CAS:

127-07-1

Masa cząsteczkowa:

76.05

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750138

MDL number:

MFCD00007943

Beilstein/REAXYS Number:

1741548

eCl@ss:

25140904

Informacje o cenach i dostępności nie są obecnie dostępne.

Pomoc techniczna

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Pozwól nam pomóc

Właściwości

grade

pharmaceutical primary standard

agency

USP

API family

hydroxyurea

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)
pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

NC(=O)NO

InChI

1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)

InChI key

VSNHCAURESNICA-UHFFFAOYSA-N

Gene Information

human ... RRM1(6240), RRM2(6241), RRM2B(50484)

Opis

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Anti-neoplastic. Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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Ta pozycja	PHR2629	400046	Y0000119
USP 1332000 Hydroxyurea	Supelco PHR2629 Hydroksymocznik	Sigma-Aldrich 400046 Hydroxyurea	Y0000119 Hydroxycarbamide
description United States Pharmacopeia (USP) Reference Standard	description Pharmaceutical Secondary Standard; Certified Reference Material	description Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase.	description European Pharmacopoeia (EP) Reference Standard
manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename Calbiochem^®	manufacturer/tradename EDQM
grade pharmaceutical primary standard	grade pharmaceutical secondary standard, certified reference material	grade -	grade pharmaceutical primary standard
format neat	format -	format -	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical small molecule	application(s) -	application(s) pharmaceutical (small molecule)
Gene Information human ... RRM1(6240), RRM2(6241), RRM2B(50484)	Gene Information -	Gene Information -	Gene Information human ... RRM1(6240), RRM2(6241), RRM2B(50484)
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C

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Piktogramy

GHS08

Słowo ostrzegawcze

Danger

Kody zagrożeń

H340,H361

Ostrzeżenia

P201 - P280 - P308 + P313

Hazard Classifications

Muta. 1B - Repr. 2

Klasa składowania

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Co się dzieje?

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)