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RUNX2

runt-related transcription factor 2

Synonimy:
AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(860) Summary: This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008]
  • Mouse(12393) runt related transcription factor 2
  • Rat(367218) runt-related transcription factor 2
  • Goat(100861217) runt-related transcription factor 2
  • domestic guinea pig(100734175) runt-related transcription factor 2
  • cow(536911) runt-related transcription factor 2
  • chicken(373919) runt-related transcription factor 2
  • Domestic Rabbit(100008943) runt-related transcription factor 2
  • Horse(100033890) runt-related transcription factor 2
  • domestic cat(101089612) runt-related transcription factor 2
  • sheep(101115489) runt-related transcription factor 2
  • dog(474923) runt-related transcription factor 2
  • dog(449531) runt-related transcription factor 2
  • naked mole-rat(101724767) runt-related transcription factor 2

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-RUNX2 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
bovine, dog, guinea pig, human, mouse, rabbit, rat
Zastosowanie
western blot
Przeciwciało anty-RUNX2, klon AS110, clone AS110, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
western blot
Anti-RUNX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-RUNX2 antibody produced in mouse, clone 4D5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-RUNX2 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human RUNX2,
Gatunek
human