SHC1
SHC (Src homology 2 domain containing) transforming protein 1
Synonimy:
SHC, SHCA
Gatunek:
Human SHC1 (6464), Mouse Shc1 (20416), Rat Shc1 (85385), Zebrafish shc1 (323818), naked mole-rat Shc1 (101717434), domestic guinea pig Shc1 (100734561), cow SHC1 (507196), sheep SHC1 (101113548), Horse SHC1 (100063053), domestic cat SHC1 (101092911) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(6464) Summary: This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
- Mouse(20416) src homology 2 domain-containing transforming protein C1
- Rat(85385) SHC (Src homology 2 domain containing) transforming protein 1
- Zebrafish(323818) SHC (Src homology 2 domain containing) transforming protein 1
- naked mole-rat(101717434) SHC (Src homology 2 domain containing) transforming protein 1
- domestic guinea pig(100734561) SHC (Src homology 2 domain containing) transforming protein 1
- cow(507196) SHC (Src homology 2 domain containing) transforming protein 1
- sheep(101113548) SHC (Src homology 2 domain containing) transforming protein 1
- Horse(100063053) SHC (Src homology 2 domain containing) transforming protein 1
- domestic cat(101092911) SHC (Src homology 2 domain containing) transforming protein 1
- dog(490439) SHC (Src homology 2 domain containing) transforming protein 1
- chicken(395934) SHC (Src homology 2 domain containing) transforming protein 1
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-SHC antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-SHC antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SHC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry