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STAT6

signal transducer and activator of transcription 6, interleukin-4 induced

Synonimy:
D12S1644, IL-4-STAT, STAT6B, STAT6C
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(6778) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20852) signal transducer and activator of transcription 6
  • Rat(362896) signal transducer and activator of transcription 6, interleukin-4 induced
  • domestic cat(101089873) signal transducer and activator of transcription 6, interleukin-4 induced
  • chicken(100859196) signal transducer and activator of transcription 6, interleukin-4 induced
  • dog(100142679) signal transducer and activator of transcription 6, interleukin-4 induced
  • sheep(101102134) signal transducer and activator of transcription 6, interleukin-4 induced
  • cow(353105) signal transducer and activator of transcription 6, interleukin-4 induced
  • Horse(100050053) signal transducer and activator of transcription 6, interleukin-4 induced
  • Zebrafish(337413) signal transducer and activator of transcription 6, interleukin-4 induced
  • domestic guinea pig(100726686) signal transducer and activator of transcription 6, interleukin-4 induced
  • naked mole-rat(101725744) signal transducer and activator of transcription 6, interleukin-4 induced
  • Domestic Rabbit(100344264) signal transducer and activator of transcription 6, interleukin-4 induced

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Phosphotyrosine STAT6 / Signal Transducer and Activator of Transcription 6 ELISA Kit, ,
Gatunek
human
Cell-Based ELISA for detecting phospho-STAT6 (pTyr641) in cultured cell lines, 96 assays,
Gatunek
mouse, human
Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines, 192 assays,
Gatunek
mouse, rat, human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-STAT6 antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

western blot
Anti-STAT6 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
Przeciwciało anty-fosfo-STAT6-Y641produkowane u królika, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało anty-fosfo-STAT6 (Tyr641), Upstate®, from rabbit,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Przeciwciało anty-fosfo STAT6 (Tyr641), klon 19E2.1, clone 19E2.1, from mouse,
Reaktywność gatunkowa
human, mouse
Zastosowanie
flow cytometry
western blot

Proteins

Numer produktu
Opis
Gatunek
STAT6, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Stat6,
Gatunek
mouse
MISSION® esiRNA, targeting human STAT6,
Gatunek
human