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Merck

TOP1MT

topoisomerase (DNA) I, mitochondrial

Synonimy:
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(116447) Summary: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(72960) DNA topoisomerase 1, mitochondrial
  • Rat(300029) topoisomerase (DNA) I, mitochondrial
  • domestic guinea pig(100728586) topoisomerase (DNA) I, mitochondrial
  • Zebrafish(415098) mitochondrial topoisomerase I
  • cow(618382) topoisomerase (DNA) I, mitochondrial
  • chicken(408025) topoisomerase (DNA) I, mitochondrial
  • naked mole-rat(101726319) topoisomerase (DNA) I, mitochondrial
  • sheep(101114532) topoisomerase (DNA) I, mitochondrial

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-TOP1MT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anti-TOP1MT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Topotecan hydrochloride hydrate, ≥98% (HPLC and enzymatic),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human TOP1MT (2),
Gatunek
human
MISSION® esiRNA, targeting human TOP1MT,
Gatunek
human