176871

Enzym konwertujący angiotensynę, His Tag, ludzki, rekombinowany, komórki NSO

• Synonim(y): Hypertensinogen, Renin Substrate
• NACRES: NA.28
• UNSPSC Code: 12352200
• eCl@ss: 32160703
• Form: liquid
• Storage condition: OK to freeze

Właściwości

• form: liquid
• Quality Segment: 100
• specific activity: ≥1 unit/µg protein
• storage condition: OK to freeze
• storage temp.: −70°C

Opis

General description

Recombinant, human ACE ectodomain (amino acids 30-1261) fused at the C-terminus to a HIS TAG^® sequence and expressed in NSO cells. ACE is a zinc metallopeptidase that cleaves the C-terminal dipeptide from angiotensin I to produce the potent vasopressor octapeptide angiotensin II. ACE gene polymorphism has been a recent topic in Alzheimer′s disease studies. ACE is a type I membrane protein and exists in two isoforms, somatic and germinal. By SDS-PAGE, the apparent molecular weight of the glycosylated protein appears larger to be than 120 kDa under both reducing and non-reducing conditions.

Legal Information

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

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