MAB2008

Anti-Integrin beta 3 (ITGB3/CD61) Antibody

CHEMICON^®, mouse monoclonal, SAP

• Synonim(y): CD61
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• Clone: SAP, monoclonal
• Species reactivity: human
• Application: IHC (p), WB
• Citations: 6

Właściwości

• Nazwa produktu: Anti-Integrin β3 Antibody, clone SAP, clone SAP, Chemicon^®, from mouse
• biological source: mouse
• Quality Segment: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: SAP, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NM_000212.2
• UniProt accession no.: P05106
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... ITGB3(3690)

Opis

Immunogen

Membranes of freshly isolated human platelets.

Application

Detect Integrin β3 using this Anti-Integrin β3 Antibody, clone SAP validated for use in WB, IH, IH(P).

Immunohistochemistry (frozen and fixed tissue sections) including paraffin embedded sections. {See Van Belle et al 1999, original paper detailing the use in human, paraffin tissues}

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10333228.

Western blot: recognizes ~115kDa band in reduced

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Monoclonal antibody MAB2008 is specific for the beta-3 subunit of the vitronectin receptor (VNR)J, which is expressed on endothelial cells, platelets, melanoma, and glioma cells. The antibody is of high affinity.

Physical form

Format: Purified

Purified immunoglobulin. Liquid at 1 mg/mL in 0.02M phosphate buffer, 0.25M sodium chloride, pH 7.6, containing 0.1% sodium azide as a preservative.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 12 - Non Combustible Liquids
• Co się dzieje?: WGK 1