C2648

Cholesterol 5β,6β-epoxide

≥98%

• Synonim(y): 5β,6β-Epoxycholestan-3β-ol
• Wzór empiryczny (zapis Hilla): C₂₇H₄₆O₂
• Numer CAS: 4025-59-6
• Masa cząsteczkowa: 402.65
• NACRES: NA.28
• PubChem Substance ID: 24892511
• UNSPSC Code: 12352211
• MDL number: MFCD00201258

Właściwości

• Quality Segment: 100
• assay: ≥98%
• form: powder
• functional group: epoxy
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@]3(O4)[C@H]4C2)([H])CC[C@@]5(C)[C@@]1([H])CC[C@]5([H])[C@]([H])(C)CCCC(C)C
• InChI: 1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28H,6-16H2,1-5H3
• InChI key: PRYIJAGAEJZDBO-UHFFFAOYSA-N

Opis

Application

Cholesterol 5β,6β-epoxide was used to treat PC12 cells or HepG2 and Caco-2 cells to study the effects of cholesterol oxidation.

Biochem/physiol Actions

Cholesterol 5β,6β-epoxide is an oxysterol produced as an oxidation product of cholesterol. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Faceshields, Gloves