Merck
Wszystkie zdjęcia(2)

F4018

Sigma-Aldrich

Anti-Mouse IgG (Fab specific)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonim(y):
Goat Anti-Mouse IgG (Fab specific)−Fluorescein isothiocyanate
Numer MDL:
NACRES:
NA.46

Poziom jakości

200

pochodzenie biologiczne

goat

białko sprzężone

FITC conjugate

forma przeciwciała

affinity isolated antibody

antibody product type

secondary antibodies

klon

polyclonal

forma

buffered aqueous solution

warunki przechowywania

protect from light

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200
indirect immunofluorescence: 1:64

temp. przechowywania

−20°C

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Opis ogólny

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.
IgG (immunoglobulin G) is found in four subclasses IgG1, IgG2, IgG3 and IgG4. IgG has a monomeric structure.

Specyficzność

Anti-Mouse IgG (Fab specific)-FITC antibody is specific for Fab fragment of all mouse IgG subclasses. Goat anti-Mouse IgG is conjugated to FITC and then purified by gel filtration to remove free FITC. The antibody is adsorbed with human IgG to ensure minimal cross reactivity. The conjugate shows no reactivity with mouse IgG, Fc fragment, human, bovine, or horse serum.

Immunogen

Purified mouse IgG Fab fragment

Zastosowanie

Anti-Mouse IgG (Fab specific) FITC antibody produced in goat has been used in :
  • fluorescent staining
  • immunocytochemistry
  • immunofuorescence

Działania biochem./fizjol.

IgG (immunoglobulin G) antibody provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. IgG antibody participates in complement fixation and opsonization.

Inne uwagi

Antibody adsorbed with bovine, equine and human serum proteins.

Postać fizyczna

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Uwaga dotycząca przygotowania

Adsorbed to reduce background staining with bovine, horse, or human samples.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Kod klasy składowania

12 - Non Combustible Liquids

WGK

nwg

Temperatura zapłonu °F

Not applicable

Temperatura zapłonu °C

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certyfikat analizy

Wprowadź numer partii, aby wyszukać certyfikat analizy (COA).

Świadectwo pochodzenia

Wprowadź numer partii, aby wyszukać świadectwo pochodzenia (COO).

Quotes and Ordering

Amino-terminally truncated desmin rescues fusion of des-/- myoblasts but negatively affects cardiomyogenesis and smooth muscle development
Hollrigl A, et al.
Febs Letters, 523(1-3), 229-233 (2002)
Luigi Aurisicchio et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(5), 1575-1584 (2009-02-26)
Oligodeoxynucleotides containing unmethylated CpG dinucleotides induce innate and adaptive immunity through Toll-like receptor 9 (TLR9). In the present study, we have examined the ability of a novel agonist of TLR9, called immunomodulatory oligonucleotide (IMO), to enhance effects of a HER-2/neu
Alexandra Höllrigl et al.
FEBS letters, 523(1-3), 229-233 (2002-07-19)
Desmin fulfils important functions in maintenance of muscle cells and mutations in the desmin gene have been linked to a variety of myopathies. To ascertain the role of desmin's amino-terminal domain in muscle cells we generated embryonic stem cells constitutively
Changes in erythropoiesis in hereditary hemochromatosis are not mediated by HFE expression in nucleated red cells
Feeney GP, et al.
Haematologica, 90(2), 180-187 (2005)
Complex regulation of spiral ganglion neuron firing patterns by neurotrophin-3
Zhou Z, et al.
The Journal of Neuroscience, 25(33), 7558-7566 (2005)

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