K4393

PKCι, active, GST tagged human

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Synonim(y): DXS11 79 E, PRKCl
• NACRES: NA.32
• UNSPSC Code: 51111800
• Specific activity: 564-764 nmol/min·mg
• Assay: ≥70% (SDS-PAGE)
• Recombinant: expressed in baculovirus infected Sf9 cells

Właściwości

• recombinant: expressed in baculovirus infected Sf9 cells
• Quality Segment: 200
• product line: PRECISIO^® Kinase
• assay: ≥70% (SDS-PAGE)
• form: buffered aqueous glycerol solution
• specific activity: 564-764 nmol/min·mg
• mol wt: ~98 kDa
• UniProt accession no.: P41743
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... PRKCI(5584)

Opis

General description

PKCι (protein kinase C ι) belongs to the protein kinase C family.

Biochem/physiol Actions

Protein kinase C ι (PKCι) is involved in Ras signaling. In colonic epithelium, it is an important regulator of oncogenic Ras. Transgenic mice which are constitutively expressing PKCι are at high risk of carcinogen-mediated colon carcinogenesis.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids
• Co się dzieje?: WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)