SML3581

NVP-ACQ090

≥98% (HPLC)

• Synonim(y): 1-[[(4S,4aS,8aR)-Decahydro-2-[(2S)-3-(6-methoxy-3-pyridinyl)-2-methylpropyl]-4-isoquinolinyl]carbonyl]-4-(3,4-difluorophenyl)-piperazine, ACQ 090, ACQ-090, ACQ090, [(4S,4aS,8aR)-Decahydro-2-[(2S)-3-(6-methoxy-3-pyridinyl)-2-methylpropyl]-4-isoquinolinyl][4-(3,4-difluorophenyl)-1-piperazinyl]methanone, [4-(3,4-Difluoro-phenyl)-piperazine-1-yl]-{(4S,4aS,8aR)-2[(S)-3-(6-methoxy-pyridin-3-yl)-2-methyl-propyl]-decahydroisoquinoline-4-yl}-methanone
• Wzór empiryczny (zapis Hilla): C₃₀H₄₀F₂N₄O₂
• Numer CAS: 362612-47-3
• Masa cząsteczkowa: 526.66
• NACRES: NA.77
• UNSPSC Code: 51111800
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C

Opis

Biochem/physiol Actions

NVP-ACQ090 is a non-peptidic, potent and subtype-selective somatostatin (SRIF; somatotropin release-inhibiting factor) receptor (SST3; SSTR3) antagonist (hSST3 pKD = 8.15, hSSTR1/2/4/5 pKD = 5.69/5.34/5.83/5.95). NVP-ACQ090 blocks hSST3 phosphorylation induced by somatostatin-14 (SS-14) in cultures and impaires object recognition in wild-type mice in vivo (50 μg/kg i.p.).

Non-peptidic, potent and subtype-selective somatostatin (SRIF; somatotropin release-inhibiting factor) receptor (SST3; SSTR3) antagonist in vitro and in vivo

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable