W108

WAY-100635 maleate salt

5-HT1A serotonin receptor antagonist, powder

• Synonim(y): N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate salt
• Wzór empiryczny (zapis Hilla): C₂₅H₃₄N₄O₂ · C₄H₄O₄
• Numer CAS: 634908-75-1
• Masa cząsteczkowa: 538.64
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278113
• NACRES: NA.77
• MDL number: MFCD01321056
• Form: powder

Właściwości

• Nazwa produktu: WAY-100635 maleate salt, powder
• form: powder
• Quality Segment: 100
• color: white
• solubility: H₂O: 25 mg/mL
• SMILES string: [H]\C(=C(/[H])C(O)=O)C(O)=O.COc1ccccc1N2CCN(CC2)CCN(C(=O)C3CCCCC3)c4ccccn4
• InChI: 1S/C25H34N4O2.C4H4O4/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21;5-3(6)1-2-4(7)8/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: XIGAHNVCEFUYOV-BTJKTKAUSA-N
• Gene Information: human ... HTR1A(3350)

Opis

Application

WAY-100635 maleate salt has been used as a 5-HT1A serotonin receptor antagonist:

• to study whether the behavior of the cleaner wrasse is regulated by serotonin activity
• to block activity of 3,4 methylenedioxymethamphetamine (MDMA) used to induce oxytocin release in male Wistar rats to increase their social behavior
• to study the role of serotonin during metamorphosis of the ascidian Phallusia mammillata larvae

Biochem/physiol Actions

WAY-100635 maleate salt is a highly selective 5-HT1A serotonin receptor antagonist. It has an ability to inhibit brexpiprazole, an antipsychotic drug that regulates serotonin-dopamine activity.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)