PHEX
phosphate regulating endopeptidase homolog, X-linked
Synonyms:
HPDR, HPDR1, HYP, HYP1, LXHR, PEX, XLH
Species:
Human PHEX (5251), Mouse Phex (18675), Rat Phex (25512), dog PHEX (480862), domestic cat PHEX (101084775), cow PHEX (536029), Horse PHEX (100051921), sheep PHEX (101112286), chicken PHEX (395777), domestic guinea pig Phex (100714464)
UniProtKB ID:
Gene ID:
- Human(5251) Summary: The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. [provided by RefSeq, Jul 2008]
- Mouse(18675) phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
- Rat(25512) phosphate regulating endopeptidase homolog, X-linked
- dog(480862) phosphate regulating endopeptidase homolog, X-linked
- domestic cat(101084775) phosphate regulating endopeptidase homolog, X-linked
- cow(536029) phosphate regulating endopeptidase homolog, X-linked
- Horse(100051921) phosphate regulating endopeptidase homolog, X-linked
- sheep(101112286) phosphate regulating endopeptidase homolog, X-linked
- chicken(395777) phosphate regulating endopeptidase homolog, X-linked
- domestic guinea pig(100714464) phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
- Zebrafish(386969) phosphate regulating gene with homologues to endopeptidases on the X chromosome
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