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Merck

338818

Ammonium hydroxide solution

28% NH3 in H2O, ≥99.99% trace metals basis

Synonym(s):

Ammonia aqueous, Ammonia water

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About This Item

Linear Formula:
NH4OH
CAS Number:
1336-21-6
Molecular Weight:
35.05
NACRES:
NA.21
PubChem Substance ID:
329754690
eCl@ss:
38060103
UNSPSC Code:
12352106
MDL number:
MFCD00066650
Beilstein/REAXYS Number:
3587154

Key Documents

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Product Name

Ammonium hydroxide solution, 28% NH3 in H2O, ≥99.99% trace metals basis

InChI

1S/H3N.H2O/h1H3;1H2

SMILES string

[NH4+].[OH-]

InChI key

VHUUQVKOLVNVRT-UHFFFAOYSA-N

assay

≥99.99% trace metals basis

form

liquid

expl. lim.

27 %

concentration

28% NH3 in H2O

pH

11.7 (20 °C)

Quality Level

100

solubility

water: soluble

density

0.9 g/mL at 25 °C (lit.)
0.9 g/mL at 25 °C

storage temp.

2-8°C

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Application

Ammonium hydroxide solution (28% NH3 in H2O) can be used as:
  • A medium to prepare magnetite (Fe3O4) nanoparticles via a modified controlled chemical coprecipitation method using divalent or trivalent iron salts as iron precursors.      
  • A reagent in ammonolysis.      
  • A solvent to synthesize 1, 4 dihydropyridines via one-pot condensation of an aldehyde and alkyl acetoacetate.

General description

Ammonium hydroxide solution is also called aqueous ammonia, aqua ammonia, or ammonia water. It is a weak base mainly used as a nitrogen source to prepare other nitrogen-containing organic and inorganic chemicals such as urea, ammonium carbonate, ammonium sulfate, etc.

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ5677
MKCV7177
MKCW8983
0000268851
MKCT5941

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Shelley Stafford et al.
Nanomaterials (Basel, Switzerland), 8(12) (2018-12-16)
In this work, new magnetic-plasmonic nanocomposites have been developed through the use of two complementary polyelectrolytes⁻polystyrene sulfonate (PSS) and poly(allylamine hydrochloride) (PAH). PSS, a negatively charged polyelectrolyte, was utilized as a stabiliser for magnetite nanoparticles, and PAH, a positively charged
Mengqi Li et al.
Cell metabolism, 30(3), 508-524 (2019-06-18)
Fructose-1,6-bisphosphate (FBP) aldolase links sensing of declining glucose availability to AMPK activation via the lysosomal pathway. However, how aldolase transmits lack of occupancy by FBP to AMPK activation remains unclear. Here, we show that FBP-unoccupied aldolase interacts with and inhibits
Konstantin Chingin et al.
Analytical chemistry, 84(15), 6856-6862 (2012-07-12)
We introduce an online multiple-junction capillary isoelectric focusing fractionator (OMJ-CIEF) for separation of biological molecules in solution by pI. In OMJ-CIEF, the separation capillary is divided into seven equal sections joined with each other via tubular Nafion membrane insertions. Each
Aurélie Periat et al.
Journal of chromatography. A, 1356, 211-220 (2014-07-16)
In this study, the influence of electrospray ionization (ESI) source design on the overall sensitivity achieved in hydrophilic interaction chromatography (HILIC) and reversed phase liquid chromatography (RPLC), was investigated. State-of-the-art triple quadrupole mass analyzers from AB Sciex, Agilent Technologies and
J C Naviaux et al.
Translational psychiatry, 4, e400-e400 (2014-06-18)
Autism spectrum disorders (ASDs) now affect 1-2% of the children born in the United States. Hundreds of genetic, metabolic and environmental factors are known to increase the risk of ASD. Similar factors are known to influence the risk of schizophrenia
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