Merck
All Photos(3)

L1750

Sigma-Aldrich

L-(+)-Lactic acid

≥98%

Synonym(s):
Sarcolactic acid, (S)-2-Hydroxypropionic acid
Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
Beilstein:
1720251
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥98%

antibiotic activity spectrum

Gram-negative bacteria

Mode of action

cell membrane | interferes

storage temp.

2-8°C

SMILES string

C[C@H](O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

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General description

L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81).

Application

Lactic acid has been used:
  • as a component in substrate solution II for lactate dehydrogenase reaction
  • as an additive in storage solution A
  • as a supplement in the artificial gastric juice preparation for evaluation of degree of resistance Lactobacillus to the gastric stresses

Packaging

10, 100 g in glass bottle

Biochem/physiol Actions

L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110.00 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands
Davenport AP, et al.
Pharmacological Reviews, 65(3), 967-986 (2013)
Cell-free transcription of SV40
SV40 protocols, 73-73 (2001)
A History of Lactic Acid Making: A Chapter in the History of Biotechnology (1990)
The isolation, identification and analyzes of Lactobacillus genus bacteria with probiotic potential
Advances in Microbiology, Infectious Diseases and Public Health, 73-73 (2016)
Mastoparan as a G protein activator
Animal Toxins: Facts and Protocols, 120-121 (2000)

Protocols

LC/MS Analysis of Lactic Acid Enantiomers in Urine on Astec® CHIROBIOTIC® R

Separation of L-(+)-Lactic acid, analytical standard; D-(−)-Lactic acid, 93-107%

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