Skip to Content
Merck

PYR0MATCELLS

PyroMAT® cells

pkg of 2 vials, Cryopreserved MonoMac 6 cells for use in the Monocyte Activation Test (MAT) for Pyrogen testing

Sign In to View Organizational & Contract Pricing

Select a Size

About This Item

UNSPSC Code:
41116129
eCl@ss:
32160606
NACRES:
NA.74

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Agency

EP Chapter 2.6.30

Quality Level

400

feature

ready-to-use

packaging

pkg of 2 vials

manufacturer/tradename

PyroMAT®

application(s)

pharmaceutical
pyrogen testing

compatibility

configured for PyroMAT® System

shipped in

dry ice

suitability

pyrogenic bacteria

General description

The PYROMAT® system is a robust, easy-to-perform and ready-to-use solution for pyrogen testing, using the Monocyte Activation Test (MAT). The PYROMAT® cells are cryopreserved human monocytic cells from the Mono-Mac-6 cell line. They have been validated to be used for MAT.
The PyroMAT® System is based on the Mono-Mac-6 (MM6) cell line and uses Interleukin-6 (IL-6) as a read out.
PyroMATcells contains the crypreserved MonoMac 6 cells, 2 x 1 mL

Application

PYROMAT® cells is used to determine the pyrogenic activity in a solution or suspension by inducing interleukin production in cell cultures with human monocytes. It is used to ensure the safety of parenteral pharmaceutical products and medical devices.

Features and Benefits

  • Cryopreserved ready-to-use monocytic cells
  • The only cell line validated and available for the Monocyte Activation Test
  • Expression of all the Toll-like Receptors responsible for pyrogen detection

Packaging

1 box of 2 vials, sufficient for 1 test

Other Notes

2 vials of cryopreserved Mono-Mac-6 cells
Download the PyroMAT® Method Software from here.
To be used with PyroMAT kit (PYR0MATKIT), Reference standard endotoxin (144.161.0001), NEP controls (MATHKSA, MATFLAGELLIN)

Legal Information

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

原代细胞培养基础知识

什么是原代细胞？关于动物和人类原代细胞系和培养基的全面概述，以及它们如何应用于生物医学细胞培养应用。相对于细胞系，原代培养物的均一性较低。

Introduction to Primary Cell Culture

Yeast plasmid selection: Utilizes auxotrophic yeast strains for plasmid selection, enabling growth on synthetic media for better yield.

Primary Cell Culture Basics

Overview of primary cells and media usage in biomedical culture applications highlights differences from cell lines.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service