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Merck

21223

Hydroxyapatite

purum p.a., ≥90% (as Ca3(PO4)2, KT)

Synonym(s):

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

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About This Item

Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
1306-06-5
Molecular Weight:
502.31
NACRES:
NA.21
PubChem Substance ID:
57647915
UNSPSC Code:
12352300
EC Number:
215-145-7
MDL number:
MFCD00010904
Assay:
≥90% (as Ca3(PO4)2, KT)
Form:
powder

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Product Name

Hydroxyapatite, purum p.a., ≥90% (as Ca3(PO4)2, KT)

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

grade

purum p.a.

assay

≥90% (as Ca3(PO4)2, KT)

form

powder

impurities

≤5% water (KFT)

loss

≤10% loss on ignition, 800 °C

anion traces

chloride (Cl-): ≤500 mg/kg
sulfate (SO42-): ≤2000 mg/kg

cation traces

Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

Quality Level

100

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1 of 4

This Item
900203677418289396
Hydroxyapatite purum p.a., ≥90% (as Ca3(PO4)2, KT)

Sigma-Aldrich

21223

Hydroxyapatite

Hydroxyapatite powder, 10 μm

Sigma-Aldrich

900203

Hydroxyapatite

Hydroxyapatite nanopowder, <200 nm particle size (BET), ≥97%, synthetic

Sigma-Aldrich

677418

Hydroxyapatite

Hydroxyapatite powder, synthetic

Sigma-Aldrich

289396

Hydroxyapatite

form

powder

form

powder

form

nanopowder, solid

form

powder, solid

assay

≥90% (as Ca3(PO4)2, KT)

assay

-

assay

≥97%

assay

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

grade

purum p.a.

grade

-

grade

-

grade

-

impurities

≤5% water (KFT)

impurities

-

impurities

-

impurities

-

cation traces

Cd: ≤5 mg/kg, Cu: ≤20 mg/kg, Ni: ≤5 mg/kg, Zn: ≤10 mg/kg, Co: ≤5 mg/kg, Pb: ≤5 mg/kg, Fe: ≤400 mg/kg

cation traces

-

cation traces

-

cation traces

-

Application

Hydroxyapatite may be used in the preparation of bioceramic specimens by incorporation of a small amount of silicon (0.4wt%) into the structure of hydroxyapatite.[1] It may be used for the preparation of porous microstructures, having important prosthetic applications.[2]

General description

Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated.[3] Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied.[3][2]
Hydroxyapatite is a bioceramic mainly found in minerals of bone and teeth.[4] Due to its high biocompatibility and similarity with inorganic components found in hard tissues, it is mainly used to produce biocomposites and prostheses for bones and teeth replacement.[5]

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7824
BCCN0113
BCCK5328
BCCK8478
BCCK5856

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Hydroxyapatite synthesis and the benefits of its blend with calcium aluminate cement.
Oliveira IR, et al.
Ceramics International, 42(2), 2542-2549 (2016)
Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various
Sophie E P New et al.
Circulation research, 113(1), 72-77 (2013-04-26)
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute
View All Related Papers

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