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Merck

C2219000

Citric acid monohydrate

European Pharmacopoeia (EP) Reference Standard

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50 MG

$237.00

$237.00


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About This Item

Linear Formula:
HOC(COOH)(CH2COOH)2 · H2O
CAS Number:
Molecular Weight:
210.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4018641

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Product Name

Citric acid monohydrate, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2

SMILES string

OC(CC(O)(C(O)=O)CC(O)=O)=O.O

InChI key

YASYEJJMZJALEJ-UHFFFAOYSA-N

grade

pharmaceutical primary standard

agency

EP Reference Standard

API family

citric acid

manufacturer/tradename

EDQM

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

application(s)

pharmaceutical (small molecule)

format

neat

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1 of 4

This Item
PHR29031.0024433114
grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

ACS reagent

grade

ACS reagent, puriss. p.a.

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

format

neat

format

-

format

-

format

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

application(s)

-

application(s)

-

agency

EP Reference Standard

agency

traceable to Ph. Eur. C2219000, traceable to USP 1134368

agency

reag. ISO, reag. Ph. Eur.

agency

USP/NF, reag. ISO, reag. Ph. Eur.

API family

citric acid

API family

-

API family

-

API family

-

Application

Citric acid monohydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

345.0 °F - closed cup

flash_point_c

173.9 °C - closed cup


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Anne R Tinning et al.
American journal of physiology. Renal physiology, 307(11), F1215-F1226 (2014-10-24)
Both the processing and release of secretory granules involve water movement across granule membranes. It was hypothesized that the water channel aquaporin (AQP)1 directly contributes to the recruitment of renin-positive cells in the afferent arteriole. AQP1(-/-) and AQP1(+/+) mice were
Katja Sundström et al.
Endocrinology, 155(12), 4798-4807 (2014-09-23)
The growth-promoting effect of combined therapy with GH and IGF-I in normal rats is not known. We therefore investigated the efficacy of treatment with recombinant human (rh)GH and/or rhIGF-I on longitudinal bone growth and bone mass in intact, prepubertal, female
Anne Marie V Schou-Pedersen et al.
Journal of pharmaceutical and biomedical analysis, 107, 333-340 (2015-02-04)
Concentrated solutions containing 6-aminocaproic acid and the excipients citric acid and sorbitol have been studied at temperatures of 50°C, 60°C, 70°C and 80°C as well as at 20°C. It has previously been reported that the commonly employed citric acid is
Eva Wex et al.
PloS one, 10(3), e0119953-e0119953 (2015-03-18)
Excessive coughing is a common feature of airway diseases. Different G-protein coupled receptors, including β2-adrenergic receptors (β2-AR), have been implicated in the molecular mechanisms underlying the cough reflex. However, the potential antitussive property of β2-AR agonists in patients with respiratory
Leila Bagheri et al.
Journal of microencapsulation, 31(7), 636-643 (2014-04-29)
Whey proteins were inter-connected either by the enzyme transglutaminase or citric acid and then desolvated with ethanol to generate particles. Both samples comprised of sub-micron (>300 nm) and nano-scaled (~100 nm) particles based on the hydrodynamic size measurements. Enzyme-induced cross-linking

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