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Factor IX human

Name: Factor IX human
Brand: SIGMA

aqueous glycerol solution, ≥145 units/mg protein

Synonym(s):

Christmas factor, Plasma thromboplastin component

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About This Item

CAS Number:

9001-28-9

UNSPSC Code:

12352202

NACRES:

NA.61

MDL number:

MFCD00163303

Form:

aqueous glycerol solution

Biological source:

human

Mol wt:

55 kDa

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Properties

biological source

human

Quality Segment

200

form

aqueous glycerol solution

specific activity

≥145 units/mg protein

mol wt

55 kDa

technique(s)

ligand binding assay: suitable

UniProt accession no.

P00740

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... F9(2158)

Description

General description

Factor IX is a 55 kDa single chain vitamin K-dependent plasma zymogen which plays a key role in the intrinsic and extrinsic blood coagulation systems.

Application

Factor IX is plasma zymogen key to blood coagulation systems. It has been used in studies of portal vein thrombosis (PVT) in hepatocellular carcinoma (HCC). It has been found that abnormalities in factor IX contribute to PVT in HCC patients. Additionally, it has been used in studies of changes in the coagulation system in patients with inflammatory bowel disease (IBD).

Physical form

Aqueous solution containing 50% (v/v) glycerol

Other Notes

One unit is equivalent to the Factor IX activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.

View this factors role in the Coagulation Cascade

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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This Item	F0931	F0681	233279
Sigma-Aldrich F0806 Factor IX human	Sigma-Aldrich F0931 Factor Va human	Sigma-Aldrich F0681 Factor V human	Sigma-Aldrich 233279 Coagulation Factor IX, Human Plasma
description aqueous glycerol solution, ≥145 units/mg protein	description ≥1500 units/mg protein	description aqueous glycerol solution, ≥25 units/mg protein	description Coagulation Factor IX, Human Plasma, CAS 9001-28-9, is a native coagulation factor IX from human plasma. Sold on the basis of plasma equivalent units. 100 plasma equivalent units = 500 µg.
technique(s) ligand binding assay: suitable	technique(s) ligand binding assay: suitable	technique(s) ligand binding assay: suitable	technique(s) -
biological source human	biological source human	biological source human	biological source human plasma
form aqueous glycerol solution	form solution	form aqueous glycerol solution	form liquid
mol wt 55 kDa	mol wt 168 kDa	mol wt -	mol wt -
Gene Information human ... F9(2158)	Gene Information human ... F5(2153)	Gene Information human ... F5(2153)	Gene Information -
specific activity ≥145 units/mg protein	specific activity ≥1500 units/mg protein	specific activity ≥25 units/mg protein	specific activity ≥150 units/mg protein (clotting assay)

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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