O7125
L-Ornithine L-aspartate salt
≥98% (TLC)
Synonym(s):
(S)-2,5-Diaminopentanoic acid L-aspartate salt
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About This Item
Empirical Formula (Hill Notation):
C9H19N3O6
CAS Number:
Molecular Weight:
265.26
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
221-772-7
MDL number:
Product Name
L-Ornithine L-aspartate salt, powder
InChI key
IXUZXIMQZIMPSQ-ZBRNBAAYSA-N
InChI
1S/C5H12N2O2.C4H7NO4/c6-3-1-2-4(7)5(8)9;5-2(4(8)9)1-3(6)7/h4H,1-3,6-7H2,(H,8,9);2H,1,5H2,(H,6,7)(H,8,9)/t4-;2-/m00/s1
SMILES string
NCCC[C@H](N)C(O)=O.N[C@@H](CC(O)=O)C(O)=O
assay
≥98% (TLC)
form
powder
color
white to off-white
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
L-Ornithine L-aspartate is a metabolite of arginine degradation by arginase. It has been shown to reduce blood ammonia concentrations by increasing ammoniadetoxification in the muscle and reducing the severity of hepatic encephalopathy in cirrhosis.
Other Notes
Product of arginine degradation by arginase
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Suzanna Ndraha et al.
Acta medica Indonesiana, 42(3), 158-161 (2010-08-21)
Excessive protein intake can cause hepatic encephalopathy (HE). Restricting protein in HE is becoming a controversy, because it can worsen malnutrition. This article reports the case of an under nourishment HE which is treated with L-ornithine-L-aspartate (LOLA) and given appropriate
Mark J W McPhail et al.
Neurology, 80(11), 1041-1047 (2013-02-22)
To measure changes in psychometric state, neural activation, brain volume (BV), and cerebral metabolite concentrations during treatment of minimal hepatic encephalopathy. As proof of principle, 22 patients with well-compensated, biopsy-proven cirrhosis of differing etiology and previous minimal hepatic encephalopathy were
Treatment of hyperammonemia in liver failure: a tale of two enzymes.
Rajiv Jalan et al.
Gastroenterology, 136(7), 2048-2051 (2009-05-05)
B M Datsenko et al.
Klinichna khirurhiia, (4)(4), 9-12 (2013-07-31)
Comparative analysis of results of examination and treatment of 54 patients, suffering obturation jaundice syndrome, is presented. The presence and severity of hepatic dysfunction was determined in accordance to indices of cytolysis and cholestasis syndromes, and its severity--in accordance to
Babette Linde et al.
Medizinische Klinik (Munich, Germany : 1983), 102(10), 846-851 (2007-10-12)
Fulminate liver insufficiency can have many causes and is a challenge for differential diagnosis. A 39-year-old woman was admitted because of a nonitching macular-papular exanthema on both thighs with spreading to the trunk. In addition, the patient complained of dysphagia
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