Skip to Content
Merck
  • [Reactions of 1-(X-benzoyl)-4-R-thiosemicarbazide with chloroacetone and omega-bromoacetophenone. VI. 4-(o-tolyl)-thiosemicarbazide of o-nitro - and p-nitrobenzoic acid].

[Reactions of 1-(X-benzoyl)-4-R-thiosemicarbazide with chloroacetone and omega-bromoacetophenone. VI. 4-(o-tolyl)-thiosemicarbazide of o-nitro - and p-nitrobenzoic acid].

Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina (1996-01-01)
E Bielak, S Biliński
ABSTRACT

The reactions of 4-(o-tolyl)-thiosemicarbazide of o-nitro- and p-nitrobenzoic acid (Ik, l) with chloroacetone and omega-bromoacetophenone were investigated in: methanolic medium (method D); methanolic medium in the presence of anhydrous CH3COONa (method E); methanolic medium in the presence of N(C2H5)3 (method F). The properties of compounds IIu-y and IIIu-y were determined under the conditions of basic and acidic hydrolysis. The results of UV, IR and NMR spectroscopic measurements were reported.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Chloroacetone, 95%
Supelco
2-Bromoacetophenone, derivatization grade (GC derivatization), LiChropur, ≥99.0%
Sigma-Aldrich
Chloroacetone, Wacker Chemie AG, ≥96.0% (GC)
Sigma-Aldrich
2-Bromoacetophenone, 98%