- IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8
IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8
Scientific reports (2017-10-19)
Lei Li, Steven M Jay, Yan Wang, Shu-Wei Wu, Zhengguo Xiao
PMID29042682
ABSTRACT
An effective cytotoxic T lymphocyte (CTL) response against intracellular pathogens is generally accomplished by immense CTL expansion and activation, which can destroy infected cells. Vigorous immune responses can lead to activation of bystander CD8