Both D4784 ,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride and 66807 4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride are not marketed as amino acid labeling products. D4784 has a purity of 98% as determined by HPLC, while 66807 has a purity of 97% according to HPLC analysis. Both products are essentially the same.
D4784
4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride
≥98% purity (HPLC), powder
Synonym(s):
1,2-Diamino-4,5-methylenedioxybenzene dihydrochloride, 1,3-Benzodioxole-5,6-diamine dihydrochloride, 5,6-Diamino-1,3-benzodioxole dihydrochloride, MDB
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About This Item
Empirical Formula (Hill Notation):
C7H8N2O2 · 2HCl
CAS Number:
Molecular Weight:
225.07
Beilstein:
5641607
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
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Product Name
4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride, Fluorogenic reagent
Quality Level
Assay
≥98% (HPLC)
form
powder
technique(s)
titration: suitable
color
white to orange
mp
247 °C
solubility
H2O: 50 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
Cl[H].Cl[H].Nc1cc2OCOc2cc1N
InChI
1S/C7H8N2O2.2ClH/c8-4-1-6-7(2-5(4)9)11-3-10-6;;/h1-2H,3,8-9H2;2*1H
InChI key
YXEJRYIEFFUUID-UHFFFAOYSA-N
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1 of 4
This Item | 66807 | 78450 | D71607 |
|---|---|---|---|
| technique(s) titration: suitable | technique(s) - | technique(s) - | technique(s) - |
| color white to orange | color - | color - | color - |
| application(s) diagnostic assay manufacturing | application(s) - | application(s) - | application(s) - |
| form powder | form solid | form powder | form solid |
| solubility H2O: 50 mg/mL | solubility - | solubility - | solubility - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 200 |
General description
4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride is a fluorescence tag for α keto acids. It is also required for the derivatization of sialic acids in presence of dilute sulfuric acid. The method allows determination of sialic acids.[1]
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Determination of sialic acids in immune system cells (coelomocytes) of sea urchin, Paracentrotus lividus, using capillary LC-ESI-MS/MS.
Izzetoglu S, et al.
Fish & Shellfish Immunology, 36, 181-186 (2014)
Savaş İzzetoğlu et al.
Fish & shellfish immunology, 36(1), 181-186 (2013-11-13)
Coelomocytes are considered to be immune effectors of sea urchins. Coelomocytes are the freely circulating cells in the body fluid contained in echinoderm coelom and mediate the cellular defence responses to immune challenges by phagocytosis, encapsulation, cytotoxicity and the production
Determination of the type and quantity of sialic acid in the egg jelly coat of the sea urchin Paracentrotus lividus using capillary LC-ESI-MS/MS.
Yesilyurt B, et al.
Molecular Reproduction and Development, 82, 115-122 (2015)
Capillary Electrophoresis of Carbohydrates (2010)
Xiaoxiao Guo et al.
The Analyst, 145(13), 4512-4521 (2020-05-16)
The polysialyltransferases (polySTs) catalyse the polymerisation of polysialic acid, which plays an important role in tumour metastasis. While assays are available to assess polyST enzyme activity, there is no methodology available specifically optimised for identification and quantitative evaluation of potential
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When running on HPLC after labeling, which option should be chosen between D4784 4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride and 66807 4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride?
1 answer-
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