H4663
HMBA
≥98% (HPLC), solid
Synonym(s):
10-[(3-Hydroxy-4-methoxybenzylidene)]-9(10H)-anthracenone
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About This Item
Empirical Formula (Hill Notation):
C22H16O3
CAS Number:
Molecular Weight:
328.36
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Product Name
HMBA, ≥98% (HPLC), solid
InChI
1S/C22H16O3/c1-25-21-11-10-14(13-20(21)23)12-19-15-6-2-4-8-17(15)22(24)18-9-5-3-7-16(18)19/h2-13,23H,1H3
SMILES string
COc1ccc(cc1O)\C=C2\c3ccccc3C(=O)c4ccccc24
InChI key
MQLACMBJVPINKE-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
solid
solubility
DMSO: soluble 34 mg/mL
storage temp.
−20°C
Quality Level
Related Categories
Biochem/physiol Actions
HMBA is an Inhibitor of microtubule polymerization; apoptosis inducer.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Erwan Dupuis et al.
Talanta, 219, 121345-121345 (2020-09-06)
Capillary electrophoresis (CE) was hyphenated to multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) to determine the model age of a highly enriched uranium (HEU) sample using the 234U/230Th radiochronometer. The use of hydroxymethylbutyric acid (HMBA) as the CE electrolyte was
Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP.
Olson, et al.
Molecular Cell, 82, 1708-1723 (2023)
Yan Wang et al.
Pharmaceutical research, 31(12), 3538-3548 (2014-06-20)
To determine the effect of PEG modification on pharmacologic and gene delivery properties of polymeric CXCR4 antagonist based on Plerixafor. Polymeric Plerixafor (PAMD) was synthesized from Plerixafor (AMD3100) and grafted with different amounts of PEG (2 kDa). CXCR4 antagonism of the
Seung Han Son et al.
International journal of molecular sciences, 23(12) (2022-06-25)
CP2c, also known as TFCP2, α-CP2, LSF, and LBP-1c, is a prototypic member of the transcription factor (TF) CP2 subfamily involved in diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies including cancer. Despite its importance, many fundamental regulatory
Dong-Hui Xu et al.
International journal of oncology, 45(1), 264-272 (2014-05-03)
Nucleophosmin (NPM, also known as B23), mainly localized in the nucleolus, has been reported to be overexpressed in many types of human cancer, including colon, ovarian, prostate and gastric cancer. NPM was identified while screening the differential nuclear matrix proteins
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