P3B030D01

Pellicon^® 3 Cassette with Biomax^® Membrane

30 kDa, D screen, 0.11 m²

• Synonym(s): Pellicon^® 3 Cassette with BIOMAX 30 kDa Membrane, D screen, 0.11 m²
• UNSPSC Code: 23151806
• eCl@ss: 32031623

Properties

• material: composite regenerated cellulose (CRC) membrane; polypropylene (Screen (feed)); polypropylene cap (end cap); polypropylene housing
• Quality Level: 400
• product line: Pellicon^®
• storage condition: do not freeze
• parameter: 4-8 L/min-m² flow rate
• technique(s): tangential flow filtration (TFF): suitable; ultrafiltration: suitable
• H: 2.3 cm (0.92 in.)
• L: 20.6 cm (8.1 in.)
• filtration area: 0.11 m²
• size: 23 mL , Volume (feed); 7 mL , Volume (permeate)
• width: 5.6 cm (2.2 in.) ; 56 mm
• matrix: (Ultracel)
• pore size: 30 kDa pore size
• pH: 1-14
• storage temp.: 2-8°C

Description

General description

Pellicon^® 3 cassettes with Biomax membrane are the optimum tangential flow filtration (TFF) devices for the filtration of solutions containing therapeutical proteins, albumin, hormones, vaccines and growth factors. These advanced, high-performance cassettes are ideal for today′s higher titer therapeutic antibodies, higher viscosity feed formulations as well as the more demanding
filtration processes that require higher operating pressures, temperatures and
caustic cleaning regimes.
From small-scale to full-scale production, Pellicon^® 3 cassettes are designed for use in research, process scale-up/scale-down, applications development and full-scale manufacturing. The Pellicon^® 3 design and automated manufacturing process provides unbeatable performance consistency between cassette sizes. Pellicon^® 3 devices also offer greater cassette size selection for improved scale-up and scale-down process development. The streamlined design allows operators to quickly and easily handle, install and remove Pellicon^® 3 cassettes. The materials of construction are compatible with a broad range of chemical cleaning.

Application

monoclonal antibodies, recombinant and non-recombinant proteins, vaccines

Features and Benefits

• Robust, void-free membrane provides optimum product retention and performance consistency
• Unique feed screen design enables high mass transfer, flux for higher final concentration
• Fast, reliable scale up/down from lab to production scale
• Automated manufacturing delivers unbeatable performance consistency and reliability
• Easy to install and clean
• Extreme temperature and chemical compatibility

Other Notes

These products are manufactured in a facility which adheres to Good Manufacturing Practices.

Legal Information

BIOMAX is a registered trademark of Merck KGaA, Darmstadt, Germany

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1