W2020
WR-1065
≥98% (HPLC), reactive oxygen species scavenger, powder
同義詞:
2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride, WR-1065 dihydrochloride
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經驗公式（希爾表示法）:
C5H14N2S · 2HCl
CAS 編號:
分子量：:
207.16
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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產品名稱
WR-1065, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to off-white
solubility
H2O: ≥20 mg/mL
storage temp.
−20°C
SMILES string
Cl.Cl.NCCCNCCS
InChI
1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H
InChI key
XDRLRDHLCIFZIW-UHFFFAOYSA-N
Biochem/physiol Actions
WR-1065 is a cytoprotective cell-permeable ROS scavenge and an active metabolite of Amifostine.
WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.
WR-1065 is the active metabolite of the prodrug amifostine, generated by alkaline phosphatase. It is found to accumulate in many epithelial tissues. WR-1065 protects cellular membranes and DNA from free radical induced damage.
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本產品 | |||
|---|---|---|---|
| description ≥98% (HPLC) | description pharmaceutical secondary standard, certified reference material | description United States Pharmacopeia (USP) Reference Standard | description ≥98% (HPLC) |
| form powder | form - | form - | form powder |
| assay ≥98% (HPLC) | assay - | assay - | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level 100 |
| storage temp. −20°C | storage temp. -10 to -25°C | storage temp. −20°C | storage temp. room temp |
| solubility H2O: ≥20 mg/mL | solubility - | solubility - | solubility H2O: >15 mg/mL |
| storage condition desiccated | storage condition - | storage condition - | storage condition desiccated |
警示詞
Danger
危險代碼
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1
存儲類別/等級
11 - Combustible Solids
到底發生了什麼事？
WGK 3
閃點 (F)
Not applicable
閃點（°C）
Not applicable