MilliporeSigma

MAPK1

mitogen-activated protein kinase 1

Synonyms:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Species:
UniProtKB ID:
Gene ID:
  • Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26413) mitogen-activated protein kinase 1
  • Rat(116590) mitogen activated protein kinase 1
  • chicken(373953) mitogen-activated protein kinase 1
  • Zebrafish(360144) mitogen-activated protein kinase 1
  • dog(477575) mitogen-activated protein kinase 1
  • domestic cat(101087614) mitogen-activated protein kinase 1
  • sheep(101115485) mitogen-activated protein kinase 1
  • cow(327672) mitogen-activated protein kinase 1
  • naked mole-rat(101706099) mitogen-activated protein kinase 1
  • domestic guinea pig(100715180) mitogen-activated protein kinase 1

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ELISA

Product Number
Description
Species
Phosphotyrosine MAPK1 / MAPK3 ELISA Kit, ,
Species
human
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Species
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Species
rat, human, mouse

Antibodies

Product Number
Description
Species Reactivity
Application
MONOCLONAL ANTI-ERK2 antibody produced in mouse, clone 814CT5.4.2, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-MAPK1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-MAPK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-MAPK 1/2 Antibody, from rabbit,
Species Reactivity
bovine, canine, human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-ERK2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
Species
human, rat, mouse
Adenine, ≥99%,
Species
human, rat, mouse
Adenine, BioReagent, suitable for cell culture,
Species
human, rat, mouse

Proteins

Product Number
Description
Species
ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MAPK1,
Species
human