MilliporeSigma

AOC3

amine oxidase, copper containing 3

Synonyms:
HPAO, SSAO, VAP-1, VAP1
Species:
UniProtKB ID:
Gene ID:
  • Human(8639) Summary: This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
  • Mouse(11754) amine oxidase, copper containing 3
  • Rat(29473) amine oxidase, copper containing 3
  • chicken(420015) amine oxidase, copper containing 3
  • Thale Cress(822169) allene oxide cyclase 3
  • naked mole-rat(101709673) amine oxidase, copper containing 3
  • domestic guinea pig(100721976) amine oxidase, copper containing 3
  • sheep(101112335) amine oxidase, copper containing 3 (vascular adhesion protein 1)
  • cow(281002) amine oxidase, copper containing 3 (vascular adhesion protein 1)
  • Horse(100065718) amine oxidase, copper containing 3 (vascular adhesion protein 1)

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ELISA

Product Number
Description
Species
Human VAP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-AOC3 antibody produced in mouse, clone 4B8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
Anti-AOC3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-AOC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-AOC3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
4-(Trifluoromethyl)benzylamine, 97%,
Species
mouse, human
Benzylamine, purified by redistillation, ≥99.5%,
Species
mouse, human
4-Fluorobenzylamine, 97%,
Species
mouse, human
3-Phenyl-1-propylamine, 98%,
Species
mouse, human
Benzylamine, ReagentPlus®, 99%,
Species
mouse, human

Proteins

Product Number
Description
Species
VAP-1 human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
Species
human
PrEST Antigen AOC3, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Aoc3,
Species
mouse
MISSION® esiRNA, targeting human AOC3,
Species
human