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GAD2

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

Synonyms:
GAD65
Species:
UniProtKB ID:
Gene ID:
  • Human(2572) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
  • Mouse(14417) glutamic acid decarboxylase 2
  • Rat(24380) glutamate decarboxylase 2
  • domestic guinea pig(100734029) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • naked mole-rat(101698166) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • Thale Cress(842908) glutamate decarboxylase 2
  • sheep(101106448) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • chicken(395395) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • dog(487107) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • domestic cat(101082244) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • cow(512459) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • Zebrafish(550403) glutamate decarboxylase 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GAD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-GAD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2736, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GAD65 Antibody, clone 3B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-Glutamate Decarboxylase Antibody, 65 kDa isoform, clone GAD-6, clone GAD-6, Chemicon®, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-GAD65 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
canine, human, mouse, pig, porcine, rat
Application
western blot

Proteins

Product Number
Description
Species
GAD, control peptide for AB1511, ,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GAD2,
Species
human
MISSION® esiRNA, targeting mouse Gad2,
Species
mouse