GRN
granulin
CLN11, GEP, GP88, PCDGF, PEPI, PGRN
Human GRN (2896), Mouse Grn (14824), Rat Grn (29143), fruit fly grn (40962), dog GRN (480501), Horse GRN (100051035), domestic cat GRN (101100680), cow GRN (767942), sheep GRN (101115470), Domestic Rabbit GRN (100349528) ...More
- Human(2896) Summary: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
- Mouse(14824) granulin
- Rat(29143) granulin
- fruit fly(40962) grain
- dog(480501) granulin
- Horse(100051035) granulin
- domestic cat(101100680) granulin
- cow(767942) granulin
- sheep(101115470) granulin
- Domestic Rabbit(100349528) granulin
- domestic guinea pig(100135533) granulin
- naked mole-rat(101715753) granulin
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ELISA
Antibodies
Monoclonal Anti-GRN antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
human
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-GRN antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
human
ELISA
western blot
western blot
Monoclonal Anti-GRN antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5692, purified immunoglobulin, buffered aqueous glycerol solution,
human
immunohistochemistry
Monoclonal Anti-GRN antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5695, purified immunoglobulin, buffered aqueous glycerol solution,
human
immunohistochemistry
western blot
western blot
Anti-Granulin (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
human
immunofluorescence
western blot
western blot
Proteins
Progranulin mouse, recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE),
mouse