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MAPK9

mitogen-activated protein kinase 9

Synonyms:
JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK
Species:
UniProtKB ID:
Gene ID:
  • Human(5601) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
  • Mouse(26420) mitogen-activated protein kinase 9
  • Rat(50658) mitogen-activated protein kinase 9
  • Zebrafish(100149273) mitogen-activated protein kinase 9
  • chicken(395983) mitogen-activated protein kinase 9
  • cow(534125) mitogen-activated protein kinase 9
  • domestic cat(101084765) mitogen-activated protein kinase 9
  • Horse(100057961) mitogen-activated protein kinase 9
  • dog(474652) mitogen-activated protein kinase 9
  • Domestic Rabbit(100342664) mitogen-activated protein kinase 9
  • sheep(101120826) mitogen-activated protein kinase 9
  • domestic guinea pig(100714249) mitogen-activated protein kinase 9
  • naked mole-rat(101698286) mitogen-activated protein kinase 9

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Mapk9 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-MAPK9 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-MAPK9 (pThr183) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
ANTI-MAPK9 antibody produced in mouse, clone 3C12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-SAPK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
SP600125, ≥98% (HPLC),
Species
human
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
Species
human, rat, mouse
Adenine, ≥99%,
Species
human, rat, mouse
Adenine, BioReagent, suitable for cell culture,
Species
human, rat, mouse
α-Sexithiophene, ,
Species
human, rat

Proteins

Product Number
Description
Species
JNK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
JNK2α2/SAPK1a Protein, inactive, 50 g, Unactive, N-terminal His6-tagged, recombinant, full-length, human JNK2α2/SAPK1a unactive, for use in Kinase Assays.,
Species
human
JNK2α2/SAPK1a Protein, active, 10 µg, Active, N-terminal His-tagged, full length human JNK2α2/SAPK1a, for use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mapk9,
Species
mouse
MISSION® esiRNA, targeting human MAPK9,
Species
human