MilliporeSigma

ST5

suppression of tumorigenicity 5

Synonyms:
DENND2B, HTS1, p126
Species:
UniProtKB ID:
Gene ID:
  • Human(6764) Summary: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008]
  • Mouse(76954) suppression of tumorigenicity 5
  • Rat(308944) suppression of tumorigenicity 5
  • Zebrafish(323827) suppression of tumorigenicity 5
  • chicken(423055) suppression of tumorigenicity 5
  • dog(485380) suppression of tumorigenicity 5
  • domestic cat(101084477) suppression of tumorigenicity 5
  • cow(537907) suppression of tumorigenicity 5
  • Horse(100055513) suppression of tumorigenicity 5
  • sheep(101107989) suppression of tumorigenicity 5
  • Domestic Rabbit(100343783) suppression of tumorigenicity 5
  • domestic guinea pig(100732063) suppression of tumorigenicity 5
  • naked mole-rat(101725285) suppression of tumorigenicity 5

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ST5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-ST5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ST5,
Species
human
MISSION® esiRNA, targeting mouse St5,
Species
mouse