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Merck

W222119

Butyric acid

natural, ≥99%, FCC, FG

Synonym(s):

1-propane carboxylic acid, Butanoic acid, Ethyl acetic acid, Propyl formic acid

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About This Item

Linear Formula:
CH3CH2CH2COOH
CAS Number:
Molecular Weight:
88.11
FEMA Number:
2221
Council of Europe no.:
5c
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
8.005
EC Number:
203-532-3
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
906770
Organoleptic:
cheese; fruity; buttery
Grade:
FG
Fragrance grade
Halal
Kosher
natural
Agency:
follows IFRA guidelines
meets purity specifications of JECFA
Food allergen:
no known allergens

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Product Name

Butyric acid, natural, ≥99%, FCC, FG

SMILES string

CCCC(O)=O

InChI

1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)

InChI key

FERIUCNNQQJTOY-UHFFFAOYSA-N

grade

FG
Fragrance grade
Halal
Kosher
natural

agency

follows IFRA guidelines
meets purity specifications of JECFA

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117

vapor density

3.04 (vs air)

vapor pressure

0.43 mmHg ( 20 °C)

assay

≥99%

form

liquid

autoignition temp.

824 °F

expl. lim.

10 %

refractive index

n20/D 1.398 (lit.)

pH

2 (25 °C, 10 g/L)
3 (20 °C, 10 g/L)

bp

162 °C (lit.)

mp

−6-−3 °C (lit.)

density

0.964 g/mL at 25 °C (lit.)

cation traces

As: ≤3 ppm
Cd: ≤1 ppm
Hg: ≤1 ppm
Pb: ≤10 ppm

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

cheese; fruity; buttery

Quality Level

Gene Information

human ... HDAC1(3065)

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1 of 4

This Item
W222100B103500PHR3873
organoleptic

cheese; fruity; buttery

organoleptic

cheese; buttery; fruity

organoleptic

-

organoleptic

-

grade

FG, Halal, natural, Fragrance grade, Kosher

grade

FG, Fragrance grade, Halal, Kosher

grade

-

grade

certified reference material, pharmaceutical secondary standard

food allergen

no known allergens

food allergen

no known allergens

food allergen

-

food allergen

-

assay

≥99%

assay

≥99%

assay

≥99%

assay

-

documentation

see Safety & Documentation for available documents

documentation

see Safety & Documentation for available documents

documentation

-

documentation

-

agency

follows IFRA guidelines, meets purity specifications of JECFA

agency

follows IFRA guidelines, meets purity specifications of JECFA

agency

-

agency

-

General description

Butyric acid is a volatile fatty acid[1] that can be used as a flavoring agent.[2] It has fruity or cheesy flavor and is mainly found in dairy products.[3]

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

161.6 °F - closed cup

flash_point_c

72 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Burdock GA
Encyclopedia of Food and Color Additives, 1, 359-360 (1997)
Effect of fat content on odor intensity of three aroma compounds in model emulsions: ?-decalactone, diacetyl, and butyric acid.
Guyot C, et al.
Journal of Agricultural and Food Chemistry, 44(8), 2341-2348 (1996)
Effects of volatile fatty acid concentrations on methane yield and methanogenic bacteria
Wang Y, et al
Biomass and Bioenergy, 33(5), 848-853 (2009)
Gili Berkovitch et al.
Journal of medicinal chemistry, 51(23), 7356-7369 (2008-11-15)
Multifunctional acyloxyalkyl ester prodrugs of 5-aminolevulinic acid in cancer cell lines inhibited the proteasome and induced apoptosis and heme synthesis. The most potent prodrug was butyryloxymethyl 5-amino-4-oxopentanoate (1a). The metabolically released formaldehyde from the prodrugs was the dominant factor affecting
Svenja Plöger et al.
Annals of the New York Academy of Sciences, 1258, 52-59 (2012-06-27)
Butyrate production in the large intestine and ruminant forestomach depends on bacterial butyryl-CoA/acetate-CoA transferase activity and is highest when fermentable fiber and nonstructural carbohydrates are balanced. Gastrointestinal epithelia seem to use butyrate and butyrate-induced endocrine signals to adapt proliferation, apoptosis

Questions

1–2 of 2 Questions  
  1. What is the production strain of this product? Clostridium butyricum ATCC? DSM?

    1 answer
    1. This product is manufactured by the fermentation of sugarcane. Any additional manufacturing details are considered proprietary.

      Helpful?

  2. What is production strain of this product? I confirmed that this product was made through fermentation of Clostridium B. Clostridium butyricum ATCC 19398? C. tyrobutyricum ATCC 25755?

    1 answer
    1. The production and manufacturing is considered proprietary.

      Helpful?

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