1.37036

di-Sodium hydrogen phosphate dihydrate

EMPROVE^® EXPERT, Ph. Eur., BP, USP

• Synonym(s): di-Sodium hydrogen phosphate dihydrate, Sodium monohydrogen phosphate, Sodium phosphate dibasic, sec-Sodium phosphate, Disodium hydrogen phosphate dihydrate, Disodium phosphate, Sodium phosphate dibasic dihydrate
• Linear Formula: Na₂HPO₄ · 2H₂O
• CAS Number: 10028-24-7
• Molecular Weight: 177.99
• MDL number: MFCD00149182
• UNSPSC Code: 12352302
• EC Index Number: 231-448-7

Properties

• Agency: BP; Ph. Eur.; USP
• Quality Level: 500
• description: EMPROVE^® EXPERT Ph Eur,BP,USP
• product line: EMPROVE^® EXPERT
• form: solid
• feature: RNase and DNase free
• pH: 8.9-9.2 (5% in H₂O)
• mp: 92.5 °C (Elimination of water of crystallisation)
• solubility: 93 g/L
• density: 2.1 g/cm³ at 20 °C
• application(s): liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical
• storage temp.: 15-25°C
• SMILES string: O.O.[Na+].[Na+].OP([O-])([O-])=O
• InChI: 1S/2Na.H3O4P.2H2O/c;;1-5(2,3)4;;/h;;(H3,1,2,3,4);2*1H2/q2*+1;;;/p-2
• InChI key: KDQPSPMLNJTZAL-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate dihydrate is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, di-Sodium hydrogen phosphate dihydrate Emprove^® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable