S7672

Sarcosine

Name: Sarcosine
Brand: SIGMA

≥98%, suitable for HPLC, BioXtra

Synonym(s):

N-Methylglycine

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About This Item

Linear Formula:

CH₃NHCH₂COOH

CAS Number:

107-97-1

Molecular Weight:

89.09

NACRES:

NA.26

PubChem Substance ID:

24899761

UNSPSC Code:

12352106

EC Number:

203-538-6

MDL number:

MFCD00004279

Beilstein/REAXYS Number:

1699442

Key Documents

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Product Name

Sarcosine, BioXtra

assay

≥98%

form

powder

InChI key

FSYKKLYZXJSNPZ-UHFFFAOYSA-N

InChI

1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)

SMILES string

CNCC(O)=O

product line

BioXtra

technique(s)

HPLC: suitable

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

color

white

mp

208-212 °C (dec.) (lit.)

solubility

H₂O: 1 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.5%
sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.0005%
NH₄⁺: ≤0.1%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

application(s)

cell analysis

Quality Level

200

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Related Categories

Amino Acids

Biochemicals

Cell Culture Supplements & Reagents

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Show Differences

1 of 4

This Item	84532	131776	SAB1403059
Sigma-Aldrich S7672 Sarcosine	Sigma-Aldrich 84532 Sarcosine	Sigma-Aldrich 131776 Sarcosine	Sigma-Aldrich SAB1403059 Monoclonal Anti-KBTBD10 antibody produced in mouse
form powder	form powder with small lumps	form powder or crystals	form buffered aqueous solution
technique(s) HPLC: suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable	technique(s) capture ELISA: suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL
assay ≥98%	assay ≥98.0% (T)	assay 98%	assay -
product line BioXtra	product line -	product line -	product line -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
solubility H₂O: 1 M, clear, colorless	solubility -	solubility -	solubility -

Application

Glyphosate resistance and biodegradation by Burkholderia cenocepacia CEIB S5-2.: This study explores the role of sarcosine in glyphosate resistance and biodegradation by Burkholderia cenocepacia CEIB S5-2, highlighting its potential in environmental biotechnology (Díaz-Soto et al., 2024).

CYP116B5-SOX: An artificial peroxygenase for drug metabolites production and bioremediation.: Sarcosine is utilized in developing a novel artificial peroxygenase, enhancing bioremediation and drug metabolite production applications (Giuriato et al., 2024).

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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The startle disease mutation α1S270T predicts shortening of glycinergic synaptic currents.

Zhiyi Wu et al.

The Journal of physiology, 598(16), 3417-3438 (2020-05-24)

Loss-of-function mutations in proteins found at glycinergic synapses, most commonly in the α1 subunit of the glycine receptor (GlyR), cause the startle disease/hyperekplexia channelopathy in man. It was recently proposed that the receptors responsible are presynaptic homomeric GlyRs, rather than

Sarcosine in prostate cancer tissue is not a differential metabolite for prostate cancer aggressiveness and biochemical progression.

Florian Jentzmik et al.

The Journal of urology, 185(2), 706-711 (2010-12-21)

Sarcosine in prostate cancer tissue samples was recently reported to be increased during prostate cancer progression to metastasis and suggested to be a key metabolite of cancer cell invasion and aggressiveness. We reevaluated sarcosine in prostate cancer tissue samples as

North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study.

Simone J P M Eussen et al.

The British journal of nutrition, 110(2), 363-374 (2012-12-12)

Different lifestyle patterns across Europe may influence plasma concentrations of B-vitamins and one-carbon metabolites and their relation to chronic disease. Comparison of published data on one-carbon metabolites in Western European regions is difficult due to differences in sampling procedures and

Expression profiling of cardiac genes in human hypertrophic cardiomyopathy: insight into the pathogenesis of phenotypes.

D S Lim et al.

Journal of the American College of Cardiology, 38(4), 1175-1180 (2001-10-05)

The goal of this study was to identify genes upregulated in the heart in human patients with hypertrophic cardiomyopathy (HCM). Hypertrophic cardiomyopathy is a genetic disease caused by mutations in contractile sarcomeric proteins. The molecular basis of diverse clinical and

Evasion from accelerated blood clearance of nanocarrier named as "Lactosome" induced by excessive administration of Lactosome.

Eri Hara et al.

Biochimica et biophysica acta, 1830(8), 4046-4052 (2013-04-03)

Nanoparticle of Lactosome, which is composed of poly(l-lactic acid)-base depsipeptide with diameter of 35nm, accumulates in solid tumors by the enhanced permeability and retention (EPR) effect. However, a pharmacokinetic alteration of Lactosome was observed when Lactosome was repeatedly administered. This

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