SML0133

Nomegestrol acetate

≥98% (HPLC)

• Synonym(s): 17-Acetoxy-6-methyl-19-norpregna-4,6-diene-3,20-dione, NOMAc, Org 10486-0
• Empirical Formula (Hill Notation): C₂₃H₃₀O₄
• CAS Number: 58652-20-3
• Molecular Weight: 370.48
• UNSPSC Code: 51111800
• PubChem Substance ID: 329825183
• EC Number: 261-379-8
• MDL number: MFCD00941390

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥7 mg/mL
• storage temp.: 2-8°C
• SMILES string: CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C)C(C)=O
• InChI: 1S/C23H30O4/c1-13-11-20-18(17-6-5-16(26)12-19(13)17)7-9-22(4)21(20)8-10-23(22,14(2)24)27-15(3)25/h11-12,17-18,20-21H,5-10H2,1-4H3/t17-,18-,20-,21+,22+,23+/m1/s1
• InChI key: IIVBFTNIGYRNQY-YQLZSBIMSA-N

Description

Biochem/physiol Actions

Nomegestrol acetate (NOMAc) is a potent, highly selective progestogen, a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors. It shows potent antigonadotropic activity mediated at the hypothalamic and pituitary level with strong antiestrogenic effects and a partial antiandrogenic effect. NOMAc is used in various formulations as a contraceptive.

Progestogen, contraceptive

Safety Information

• Pictograms: GHS08,GHS09
• Signal Word: Warning
• Hazard Codes: H361fd,H400
• Precautionary Statements: P201 - P273 - P308 + P313
• Hazard Classifications: Aquatic Acute 1 - Repr. 2
• Storage Class: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable